Q. Zhang and Y. W. Leung, " Orthogonal Genetic Algorithm for Multimedia Multicast Routing." , IEEE Trans on Evolutionary Computation, Vol. 3, No. 1, 1999.
Perhaps, this paper is the first work that combines experimental design and genetic operators. If you know any other earlier papers on this issue, please let me know. Now a number of combinations of experimental design and evolutionary algorithms have been proposed and reported.
Our main idea is based on the observation that some major steps in the genetic algorithm can be considered to be "experiments." For example, the sampling of genes from the parents for crossover can be considered to be an experiment. If we apply the sophisticated experimental design methods to strengthen these experiments, the resulting genetic algorithms can be statistically sound and have a better performance.
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last updated March, 2006, Q. Zhang